Prader-Willi Syndrome (PWS) is a rare genetic disorder resulting from the loss of function of certain genes on chromosome 15. It is characterized by low muscle tone, intellectual disability, behavioral issues, and an insatiable appetite that can lead to obesity. Early intervention with therapies like growth hormone treatment and behavioral support is crucial in managing symptoms. While there is no cure, ongoing research into the genetic mechanisms of PWS offers hope for more effective therapies in the future.